Farah, who won the 5,000m and 10,000m in Barcelona in July, is fixed by reigning European and Commonwealth triple jump champion Phillips Idowu.
Christine Ohuruogu, who won Olympic 400m gold in Beijing in 2008, will also protect her Commonwealth title. Lisa Dobriskey will look to duplicate her 1500m win from Melbourne in 2006.
The 26-year-old from Kent, who won her first major medal at the Commonwealths four years ago and added a silver at the World Championships in Berlin last year, will also fight in the 800m. But she missed out on a medal at the European Championships in Barcelona.
"To preserve my title would mean a lot to me and the more racing experience I can get in championship events the better," she said. "Other than next year's World Championships, there are extremely few such opportunities between now and London 2012."
Craig Hunter, chef de assignment for England in Delhi, added: "I'm delighted to welcome such a strong group of track and field athletes into the England team for Delhi and look forward to their performances there - especially after such a dramatic European Championships."
"After an wonderful season, two gold medals in the European Championships and a new British 5,000m record, I hope to finish a fantastic summer season with one more good performance in India," he said. He said: "It's been a great season so far and I look to go to India and win another gold medal."
England won six gold, four silver and eight bronze athletics medals at the 2006 Commonwealth Games in Melbourne. The 2010 Games run from 3-14 October and feature 17 sports.